Publications

Baylor Research Group

O.O. Fagbohun, M.A. Canfield, J.A. Clinger. Crystal structure of apo human spermidine synthase reveals dynamic rearrangement at the active site. Struct. Dyn. 2026, 13 (1): 014701. https://doi.org/10.1063/4.0001199
J.R. Patel, T.J. Bonzon, T.F. Bakht, O.O. Fagbohun, J.A. Clinger. Multi-Temperature Crystallography of S-Adenosylmethionine Decarboxylase Observes Dynamic Loop Motions. Biomolecules 2025, 15, 1274. https://doi.org/10.3390/biom15091274
P.C. Obiako, B.A. Taylor, J.A. Clinger, C.M. Sayes. Perfluorooctanoic Acid, Perfluorobutanoic Acid, and Undecafluoro-2-methyl-3-oxahexanoic Acid Disrupt Neurotransmitter Release and Cholinesterase Activity. Chemosphere 2025, 387, 144678. https://doi.org/10.1016/j.chemosphere.2025.144678

Prior Work

J.A. Clinger, Y. Zhang, Y. Liu, M.D. Miller, R.E. Hall, S.G. Van Lanen, G.N. Phillips Jr., J.S. Thorson, S.I. Elshahawi. Structural and functional characterization of two cooperative enzymes responsible for the stability of p-terphenyls. ACS Chem. Bio. 2021, 16, 2816-2824. DOI: 10.1021/acschembio.1c00701

T. Engstrom, J.A. Clinger, K. Spoth, D. Closs, R.E. Thorne. High-resolution single particle cryo-EM of samples vitrified in boiling nitrogen. IUCrJ 2021, 8, 867-877. DOI: 10.1107/S2052252521008095

J.A. Clinger, D.W. Moreau, M.J. Mcleod, T. Holyoak, R.E. Thorne. Millisecond Mix-and-Quench Crystallography (MMQX) Enables Time-Resolved Studies of PEPCK with Remote Data Collection. IUCrJ 2021, 8, 784-792. DOI: 10.1107/S2052252521007053

J.A. Clinger, E. Chen, D.S. Kliger, G.N. Phillips Jr. Pump-probe circular dichroism spectroscopy of Cyanobacteriochrome TePixJ yields insights into its photoconversion. J. Phys Chem B 2021, 125, 202-210. DOI: 10.1021/acs.jpcb.0c04822

J.A. Clinger, X. Wang, W. Cai, Y. Zhu, M.D. Miller, C.-G. Zhan, S.G. Van Lanen, J.S. Thorson, G.N. Phillips Jr. The crystal structure of AbsH3: A putative FAD-dependent reductase in the Abyssomicin biosynthesis pathway. Proteins: Structure, Function, and Bioinformatics 2021, 89, 132-137. DOI: 10.1002/prot.25994

T.D. Huber, J.A. Clinger, Y. Liu, W. Xu, M.D. Miller, G.N. Phillips Jr., J.S. Thorson. Methionine Adenosyltransferase engineering to enable bioorthogonal platforms for AdoMetutilizing enzymes. ACS Chem. Bio. 2020, 15, 695-705. DOI: 10.1021/acschembio.9b00943

E.S. Burgie*, J.A. Clinger*, M.D. Miller, A.S. Brewster, P. Aller, A. Butryn, F.D. Fuller, S. Gul, I.D. Young, C.C. Pham, I.-S. Kim, A. Bhowmick, L.J. O’Riordan, K.D. Sutherlin, J.V. Heinemann, A. Batyuk, R. Alonso-Mori, M.S. Hunter, J.E. Koglin, J. Yano, V.K. Yachandra, N.K. Sauter, A.E. Cohen, J. Kern, A.M. Orville, G.N. Phillips Jr., R.D. Vierstra. Photoreversible interconversion of a phytochrome photosensory module in the crystalline state. Proc. Nat. Acad. Sci. USA 2020, 117, 300-307. DOI: 10.1073/pnas.1912041116 *co-first authors

F.D. Fuller, S. Gul, R. Chatterjee, E.S. Burgie, I.D. Young, H. Lebrette, V. Srinivas, A.S. Brewster, T. Michaels-Clark, J.A. Clinger, B. Andi, M. Ibrahim, E. Pastor, C. de Lichtenberg, R. Hussein, C.J. Pollock, M. Zhang, C.A. Stan, T. Kroll, T. Fransson, C. Weninger, M. Kubin, P. Aller, L. Lassalle, P. Brauer, M.D. Miller, M. Amin, S. Koroidov, CG. Roessler, M. Allaire, R.G. Sierra, P.T. Docker, J.M. Glowina, S. Nelson, J.E. Koglin, D. Zhu, M. Chollet, S. Song, H. Lemke, M. Liang, D. Sokaras, R. Alonso-Mori, A. Zouni, J. Messinger, U. Bergmann, A.K. Boal, J.M. Bollinger Jr., C. Krebs, M. Hogborn, G.N. Phillips Jr., R.D. Vierstra, N.K. Sauter, A.M. Orville, J. Kern, V.K. Yachandra, J. Yano. Drop-on-demand sample delivery for studying biocatalysts in action at X-ray free-electron lasers. Nat. Methods 2017, 14, 443-449. DOI: 10.1038/nmeth.4195

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